This is actually my first one. I'm only in Oklahoma, but strangely enough I've never heard of Quakecon. Never was too huge into the FPS/Lan crowd to know much about such things.
I will be going to quakecon this year, it's my 10th event. I've missed only the very first QuakeCon (didn't know it existed - heard about it during a game of net quake in '96)